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New research shows that all dog breeds come from the gray wolf – Alberton Record.

Dogs and humans have been living together for at least 15 000 years.

Dogs were domesticated thousands of years ago as companions to humans and bred for different traits. The desired traits changed over the centuries resulting in different breeds.

As humans migrated to different places on the planet over the millennia, their dogs went with them.

A team of researchers has assembled the most comprehensive genomic map on dogs to date. The results were published in the journal Cell Reports.

Researchers gathered blood samples or mouth scrapings from 1,346 dogs, of 161 breeds, over the course of 20 years. The dogs came from Europe, North America, Africa, and Asia.

For example, herding dogs, such as shepherds, collies and shelties, cluster into one clade, whereas hunting dogs, such as retrievers and setters, cluster into another clade.

This clustering indicates that dogs were originally bred for specific purposes before breeders began selecting for specific physical traits that are commonly associated with distinct breeds today.

It seems that people started breeding dogs for particular traits in multiple places at once. For instance, with the advent of agriculture, humans in multiple places in the world employed dogs for herding and guarding livestock.

When dog fighting was a popular form of entertainment, many combinations of terriers and mastiff or bully-type breeds were crossed to create dogs that would excel in the fighting ring. In this analysis, all of the bull and terrier crosses go back to the terriers of Ireland 18601870.

Later on, dogs were bred for more specific tasks. Golden Retrievers, Irish Setters, and other gun dogs, can be traced to Victorian England where these breeds were bred as retrievers, helpers and companions to hunters.

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New research shows that all dog breeds come from the gray wolf – Alberton Record.

Helping paraplegic dog heal – INFORUM

Our current dog “fell” off a 30-foot deck and severely injured his spine. We are grateful to his former family who got him the neurosurgery and then gave him up six months later. We were his fourth home in three years, and we are so blessed to have him as part of our family.

Chuckie arrived in a drag bag, secured in a weenie wrap because he had no bowel control. Although our vet was negative at our first appointment, he referred us to a canine rehabilitation center. At the initial evaluation, Chuckie demonstrated no movement from his withers to the tip of his tail, although he could drag himself quickly across the floor to a carpet and flip up onto his front legs and stand for about a minute in full, back-leg spastic extension. The center drew up a therapeutic plan, and we supplemented his diet with vitamin B-complex, a multivitamin, ArthAway and dimethylglycine.

Chuckie has made remarkable progress in spite of suffering a slipped cervical disc, which, during four weeks of screaming in pain, not one specialist could diagnose with repeated exams, X-rays and two MRIs. We found a canine chiropractor who knew immediately (based on the X-rays) and began treatment. Chuckie now receives a chiropractic adjustment once a month, and has swim, boogie board and treadmill therapy two to three times a week.

Every time we think our dog has reached his maximum potential, he surprises us. Currently, Chuckie is walking in his wheelie in the pool in a back brace, and he is moving his back legs.

In his back brace without the wheelie support, he has taken up to 13 ataxic independent steps.

Recently, we started him on a homemade high-protein diet in an effort to help build up muscle, especially in his weaker right thigh. Dr. Fox, I know this little boy can walk! We have tried spandex shorts, bodysuits, toe lifts, back braces and considered custom bracing. Most of the brace experts do not think bracing will help. With all the expenses, I am not sure I want to sink $600 to $1,200 in custom braces that won’t help. Do you have any ideas or suggestions? This little guy is happy, funny, plays with our ever-patient cat and makes us laugh every day. Currently, he takes gabapentin, a muscle relaxer and a muscle builder at night. Any and all ideas you have to offer will be explored, and we will keep you posted. P.H.P., Arlington, Va.

Dear P.H.P.: I commend you on your compassionate efforts to improve the quality of life for this injured dog.

Until stem-cell therapy is sufficiently advanced to enable possible repair of injured spinal cords, I do not have much more to offer to facilitate your dog’s recovery potential beyond what you have already utilized. Regular swimming therapy is excellent, coupled with daily total body massage, as per my book, “The Healing Touch for Dogs.”

I would give your dog daily supplements of L-carnitine, chelated magnesium and CoQ10, and continue with the other supplements and treatments. You may wish to consider my home-prepared diet posted on my website, http://www.DrFoxVet.net. Feed Chuckie two meals a day after exercising and add turmeric and ginger and a few drops of fish oil to each meal, plus a teaspoon of unsweetened canned pineapple to facilitate digestion. I always add a little plain organic yogurt or kefir to my dog’s food as a source of beneficial probiotics.

Some people may question your dedication, spending so much effort and money on “just a dog,” but as I see it, to care is to be human regardless of species and our humanity is as endangered today as the many species that are harmed and threatened with extinction by our singular and collective inhumanity.

Send all mail to animaldocfox@gmail.com or to Dr. Michael Fox in care of Universal Uclick, 1130 Walnut St., Kansas City, MO 64106. The volume of mail received prohibits personal replies, but questions and comments of general interest will be discussed in future columns. Visit Dr. Fox’s website at http://www.drfoxvet.net.

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Helping paraplegic dog heal – INFORUM

Novel regeneration therapy available for use in UK dogs – vet times

A cell transplantation technique, historically used in human medicine with groundbreaking regenerative capabilities, has been made available to UK vets for the first time to treat a range of canine orthopaedic cases.

Originating in the medical world, the Lipogems technique was invented by Carlo Tremolada, an Italian maxillofacial plastic surgeon searching for a way to create a smoother, more viscous fat graft for filling defects and creating natural volumetric face enhancement.

Unexpectedly, patients given Lipogems experienced a significant decrease in bruising and inflammation normally associated with these procedures and demonstrated substantial regenerative effects on the underlying tissues.

Scientists identified the regenerative characteristics in Lipogems and it received US Food and Drug Administration Federal Food, Drug, and Cosmetic Act (Act) Section 510(k) clearance in 2014. A subsequent review in 2016 saw it amended to include application in orthopaedic surgery settings.

The Lipogems method is carried out in one surgical step via a single-use kit for the lipoaspiration process and deployment of adipose tissue. Micro-fragmenting adipose tissue (harvested from fat) is obtained from lipoaspirates through a non-enzymatic, mechanical process using a closed system and disposable device.

Adipose tissue is harvested using a vacuum syringe around the flank of the dog under general anaesthetic, after the region has been anaesthetised by local infiltration with sterile saline and adrenaline.

Harvested fat tissue using the Lipogems device is washed in saline and gently agitated so the pericytes detach from small vessels and activate. Cells with the stromal vascular structure of adipose tissue then act as a local scaffold to maintain regenerative activity for many months.

Vet Offer Zeira said: To colleagues who ask me, why Lipogems?, I give them this the shortest and most truthful answer whoever deals with regenerative medicine uses stem cells; whoever deals with stem cells should use Lipogems.

Dr Zeira said: The results are amazing. Dogs that suffered severe lameness manage to walk with nearly no lameness within five to six days.

Lipogems Canine chief executive Martin ffrench Blake said the objective of the Lipogems product was to favour the natural regenerative process of tissues and was used in numerous pathologies.

Crown Vet Referrals is the only clinic in the UK and Ireland to have staff trained in the Lipogems Canine technique.

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Novel regeneration therapy available for use in UK dogs – vet times

She was yellow, 11-year-old Oklahoma girl battling severe type of leukemia with a smile – kfor.com

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OKLAHOMA CITY – When you get five siblings together for a board game, the play can get competitive quickly. Today, the Asher family is playing the game ‘Sorry,’ and it’s just grateful to be all together at their Yukon home.

About one year ago, the four brothers rallied around their sister, 11-year old Mackenzie. She had been complaining for days about feeling extremely tired.

I was tired really tired! I had a lot of nausea too, Mackenzie said.

Her dad picks up the story, remembering when he dropped her at a summer camp, only to have her call an hour later saying she simply couldnt handle it.

So, I picked her up, and it was in the sunlight and I don’t know if it was the light at the moment, but I could just instantly tell that she was yellow,” said dad Jayson Asher. “She had a yellowish color to her, and it was jaundice.”

Doctors at the Childrens Hospital confirmed Mackenzie had leukemia. In her case, it was one of the most severe types of leukemia, acute myeloid leukemia, or AML.

Asher chokes up at the memory of receiving the diagnosis.

Its hard to talk about,” he said. “I mean it was a shock.

The next shock was when a predicted three-week hospital stay to start chemotherapy stretched into a seven-month medical ordeal.

Her pediatric oncologist, Dr. David Crawford, confirms her diagnosis was particularly troublesome because she had a mutation in one gene.

For Mackenzie, the things she loved to do, including ballet with friends or swimming, had to be put on hold. Round after round of chemotherapy did not wipe out the cancer cells in her blood.

She needed a stem cell transplant and, at first, that looked very promising when two individuals who signed a donor registry were found to be perfect matches. Each donor ended up backing out of the procedure.

That left doctors to consider Mackenzies mother, who was willing to do the transplant but was not a perfect match. Thankfully, the stem cell transplant worked.

Jayson said the staff at the Jimmy Everest Center for Cancer was supportive and professional the entire way through the many hard turns in Mackenzies treatment.

You know, they saved her life, he said, shedding a tear. You know, as a parent, you don’t know how to thank somebody for that.

Mackenzie has found ways to thank the doctors and nurses in her own special way, creating little packages with notes and candy. Crawford said shes touched him many times with her gifts.

Shes made many, many individualized cards for me, and I post them around proudly,” he said. “Theyre really special.

Mackenzie is back at her ballet studio, dancing with her friends. Shes able to play with the family dog and swing in the backyard.

Shell have to wait until her chemotherapy port is removed before she can swim due to a risk of infection. Shes said swimming is something shes really looking forward to again.

Her treatment is not over yet. Shes been chosen to take part in a clinical trial that will take place in August in Washington DC. The treatment she will receive is designed to boost the ability of her stem cell transplant to fight off any lingering cancer cells in her blood.

Its been a tough battle, but Mackenzie is smiling and winning.

If youd like to help children like Mackenzie fight cancer, consider donating.

‘Kids With Courage’ is sponsored by the Jimmy Everest Center.

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She was yellow, 11-year-old Oklahoma girl battling severe type of leukemia with a smile – kfor.com

Quadriplegic exemplifies meaning of her name: hope – The San Diego Union-Tribune

Disabled is how others see her. However, Kie Fujii looks in the mirror of her mind and defies the dis in the image that stares back.

*

Kie was 9 years old when she opened her eyes in that strange bed. The room was cold and quiet with glaring lights. It was scary. Tubes and wires were like tentacles. But her parents were hovering over the bed, so everything was OK.

She didnt know why she was there instead of at home. She last remembered falling asleep in the backseat. She knew nothing of the accident on the hail-slick Georgia highway.

It was only when she saw the tears in her familys eyes that she knew something was wrong.

Everyone was smiling and trying hard to have a positive face. But I could tell they were sad inside, says Kie (pronounced as key-ya).

When did you realize you couldnt move?

It was a gradual thing. I thought it was something temporary. I just remember asking my mom when I would be able to run again.

(Even at that age, Kie was a dedicated runner, sometimes getting up at dawn and running 10 laps before school. She had been invited to a national Junior Olympics event. Kie was returning home from a Georgia age-group state championship track meet when all that ended.)

*

Today, Kie sits at her familys dining room table in a light wheelchair. Her computer and cellphone are within her limited reach. She is fortunate to have greater hand usage than expected for a quadriplegic. Her ever-dutiful mother sits in an adjoining chair; she is a kind person with that deferential Japanese courtesy.

The family lives modestly in Carlsbad. Her father is gone during the week as an accountant in Los Angeles. Her mother is a part-time teacher. They are a solid family of middle-class means.

photo by Fred Dickey

Kie Fujii of Carlsbad.

Kie Fujii of Carlsbad. (photo by Fred Dickey)

Kies voice is even and velvety. Her words are well-considered before uttered. Her personality is like a placid brook. Her determination, though, is a rushing stream that washes past boulders. If told a certain goal was beyond her reach, she would smile courteously and then ignore the advice.

She says, I think at the time of the accident, my parents didnt know what spinal cord injury meant. My mom just said, Youll be able to run again, probably within a month. That kind of made me happy.

Of course, the happiness didnt last. Her running dreams ended with the prognosis.

That day came when the neurosurgeon entered the room to answer the familys questions and stunned them by saying Kie would have a 5 percent or less chance of walking again. She had to learn a big word for a third-grader: quadriplegic.

*

Were accustomed to reading about the successes of paralyzed men and women who refuse to submit to their disability and struggle for a full life. We happily salute their achievements.

What we dont see is the grit, the grind, the tedium of endless rehabilitation, the pain and dismay of their challenge that far surpasses us of able bodies.

Because a body is paralyzed doesnt mean its muscles dont feel the burn and pain; actually, much more than yours do as you follow your scampering dog up a steep hill or notch up the treadmill speed.

We all have steep hills to struggle up, for certain, but we have legs for the climb.

For 15 years, Kie has pushed to widen her narrow window of expectations by endless hours of rehab, because who knows what sweat and scientific advances can do?

In her mind, Kie has made that doctors 5 percent grow like credit card interest. Hope is not arithmetic.

Kie has worked on the whole person. She finished La Costa Canyon High School wearing academic laurels, and two years ago graduated from UC Berkeley with a degree in integrative biology with an emphasis in human biology and health science.

At that demanding university, she spent Friday evenings doing experiments with her wheelchair pushed up to a lab bench while the sociology majors were down on Telegraph Avenue doing their own experiments.

When it came time to put on the mortarboard and walk the aisle, she actually did. She fulfilled a vow by walking up to get her degree. She was assisted by two helpers, but when she looked down, those were her legs touching the ground.

A moral victory, yes, but not a miracle.

*

Berkeley was two years ago. Now, its time to take the next step still figuratively.

Kie has decided to become a physician. Given her education in integrative biology at a demanding university, why should that surprise us?

Well, for the obvious reason: dealing with that ugly old prefix dis.

She has spent months wrestling with questions: Does she want it badly enough to tackle the daunting obstacles? What will be the burden on her family, especially her mother, who is her means of transportation?

Kie is as methodical as an hourglass.

Ive been passionate about (medicine) for a really long time, but I needed to make sure I wanted it bad enough.

She even shadowed medical students and doctors through their work days to confirm in her own mind she could do the work. What she learned anchored her resolve.

It reassured me this is something Im physically capable of doing. My heart is in it. If I go step by step, this is doable. I can be a doctor.

Kie, its been said the human body is both as tough as iron and as fragile as paper.

Yeah, I can tell you thats true. The human body, a disabled body, can work in ways that are unimaginable.

Today, she will begin classes in the UC San Diego after-college premedical program. Its a year spent preparing students for the rigors and discipline of medical school.

This is my choice. I just want to show them that Im fully capable. I dont want them to have any doubts about me.

Kie says several medical specialties are quite compatible with her physical capability, including radiology, neurology and an emerging field called telemedicine, in which consultations are done by video or Skype.

I know I can relate to patients on a personal level, knowing what its like to be lying on a hospital bed with multiple tubes attached to your body and not knowing if youre going to get better. Ive done that.

Kie is at peace with her condition but has not surrendered to it. Theres nothing on Google or medical websites about stem cell research that she hasnt studied.

Kie, when youre looking for cures, theres a lot of fools gold out there.

Yeah, I know. However, theres a lot of stem cell research going on. Theres promising research out there.

In medicine, things can happen quickly. Do you have any hope of restoring your body?

Oh, definitely. I work with my trainers on a weekly basis to build muscle mass, walk on the treadmill and get on a stationary bike like a regular gym. I have a standing-frame at home, so I stand every night for a little over an hour to maintain that muscle mass and to help with blood circulation.

Kie in Japanese means hope, and in her, it blooms. She says, If you maintain your health and keep that muscle mass, then youll get more benefits out of it once you receive the stem cell.

At the time of my injury, I was told that I have almost no sensation. Now, Im able to experience more feeling when Im in pain, and when my legs are too cold or too hot. Ive been able to feel all the way down to my toes. If someone pushes the bottom of my feet, then I can feel that. Thats pretty new.

*

Kie has an issue of more immediate concern starting this week with her first classes. Because UC San Diego is so spread out, shell need her power chair. But its too big to fit in the aging family car and too heavy to put on a bumper carrier.

That means her mother will have to take her to class every day and sit through each class, then push her portable wheelchair to the next class in another building. That will necessitate her mother drastically curtailing or giving up her teaching career.

Public transportation offers a service called para-transit, but because it serves multiple patrons, going to and from college could take perhaps six hours each day, including maybe waiting in the rain.

Kie needs a wheelchair-accessible van, but she might as well wish for a magic carpet.

She will rely on financial aid and maybe student loans for her medical education. However, there are no family resources to spare for the vehicle. Public agencies that help her in other ways all consider the van to be a luxury item.

*

Kie, do you sometimes go back and forth in your hopes, like an emotional roller coaster?

She nods cautiously. Yeah. Sometimes I have really good days, and sometimes pretty bad days. But I dont see myself as a disabled person. I do the things I need or want to do. I see myself just as an ordinary 24-year-old wanting to be a physician.

Do you dream of running again?

Ive had dreams where Im in a wheelchair, and then Im holding onto the fence of the track field, and then I start walking, and then Im running again.

*

The dedicated runner doesnt do it just for fun. That would not take her around the block. The runner does it for the hurt, the burning muscles, the begging lungs. The runner does it to finish what was started with her friend the pain, the victor over her lesser self.

Run, Kie, run.

Fred Dickeys home page is freddickey.net. He believes every life is an adventure and welcomes ideas at freddickey1@gmail.com.

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Quadriplegic exemplifies meaning of her name: hope – The San Diego Union-Tribune

Stem cell therapy to treat paralytic dogs draws pet owners from across country to IVRI – Times of India

Bareilly: Dog owners from across the country, including Delhi and Gujarat, are turning up with their paralytic pets at the Indian Veterinary Research Institute (IVRI) here for stem cell therapy. Scientists treat a paralyzed dog by transplanting stem cells from healthy dogs. IVRI is the second institute in the country to offer this treatment, after Madras Veterinary College, Chennai.

According to scientists, no research has been conducted to determine the number of dogs who suffer from paralysis every year in India. However, the institute receives at least four cases every week of spinal trauma which causes paralysis in dogs. IVRI recorded 143 cases of posterior paralysis in 2016. These were treated with stem cell therapy and medicines.

If dogs are treated only with medicines, recovery is witnessed only in a few cases, said Amarpal (who goes by his first name), head and principal scientist, division of surgery, IVRI. On an average, 17% recovery rate was noted among dogs administered only medicines.

However, the best response was recorded among severely affected dogs when they were treated using stem cells, where almost all the patients responded to treatment to variable extent, said the scientist. Though we have cases where recovery was 100%, the average recovery rate is about 50%. The experiment proved the efficacy of stem cell therapy in cases of paralysis due to spinal trauma, said Amarpal.

The paralytic dog is first administered anesthesia before the stem cells are injected into its spinal cord. It takes only one session for a dog to undergo the therapy and it is discharged the same day.. After this, the owner has to bring his pet for check-ups for two or more times so that vets can monitor how the animal is responding to the treatment and if it is suffering from any reaction, said Amarpal.

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Stem cell therapy to treat paralytic dogs draws pet owners from across country to IVRI – Times of India

In the Future, You Will Have the Same Pet Your Entire Life – VICE

Near the end of my conversation with Jae Woong Wang, a researcher and spokesperson for South Korea’s Sooam Biotech, he asks me to tell the world that they shouldn’t stuff any recently deceased pets they hope to have cloned in freezers. It renders cell matter impossible to harvest, which isn’t good news if you’re in the business of cat and dog duplicates. It’s hard to let a grieving family down easy, especially after they’ve made the day-long trip across the Pacific only to discover their newly dead companion won’t be getting a genome-generated second chance.

“You have to preserve the body as long as possible without freezing,” says Wang. “That’s a mistake a lot of people make. When water freezes, it punctures all the cells, and the chances of cloning becomes extremely low. It’s a frustration we’re constantly dealing with.”

Sooam Biotech’s founder, Hwang Woo-suk, ran into significant controversy in 2004 when he fraudulently claimed to have cloned human embryos, but the company has stayed in the business for over ten years. Sooam has fulfilled contracts with the commercial farming industrycloning livestock for breeding and bottom-line purposesbut its pet cloning division is a marketplace built on a more spiritual communion. It’ll take $100,000 to reunite with a reincarnated version of an animal you loved.

Its cloning process is more straightforward than you might think. A Sooam clerk will meet you at the Seoul airport and retrieve a fingernail-length biopsy of your dead pet’s flesh. A donor dog or cat is selected from the company’s kennel. Their eggs are flushed out, gutted of their genetic information, and fused with DNA harvested from the biopsy. If the process works, the retrofitted egg is inserted into a surrogate mother. “Until the point where they actually meet the dog, [the customer] is in a very happy disbelief,” says Wang. “But once we deliver the dog, they usually burst into tears.”

The jury is still out on what a clone actually is. It’s a conundrum that’s raged ever since Dolly, the famous duplicated sheep, was brought into the world in 1996. Genetically, they’ll be a mirror image of the source animal, an asexually wrought son or daughter built in the flash of nuclear transfer. But will the clone share the same emotions or personality tics? That’s difficult to say. Research on cloned cows and pigs has shown distinct differences in personalityand even looksfrom the animal of origin to its clone.

As such, New York Magazine’s Science of Us blog called pet cloning “a laughable, extravagant waste of money,” when news broke last year that media tycoon Barry Diller and fashion mogul Diane von Furstenberg had their Jack Russell terrier cloned, even though the wealthy power couple seemed pleased with the two puppies they got as a result. And, in an interview with Scientific American, stem cell biologist Robin Lovell-Badge maintained that cloning a pet was, flatly, “stupid.” “You’re never gonna get Tibble back, or whatever,” he added.

But companies like Sooam deal in loveor more specifically, the faint chance that you might love again. Because losing a dog or a cat is really goddamn rough. “A beloved pet is much like a family member,” reads the pitch on ViaGen Pets, a Texas-based commercial cloning outlet that offers a pet-cloning service. “The unique life-enriching bond, the love and companionshipa truly special pet provides us a unique sense of comfort and life-enriching fulfillment that is nearly impossible to extend beyond your pet’s natural lifespan. Until now.”

It was a convincing enough argument for Doug and Michelle Shields, and their fluffy white Maltese, Guinevere. Gwen lived 16 and a half years before she died after a seizure. The Shields had mulled the idea of preserving her genes in the past, but it wasn’t until the fresh aftermath of her death that they made the decision to start the cloning process. (Luckily, the veterinarian put Gwen’s carcass in a refrigerator, not a freezer or a cremator.)

“We’re what you’d deem to be animal people. We have a parrot and another dog we adopted,” says Michelle. “But Gwen was just an amazing, amazing, amazing dog. Just unbelievable. She just had a personality. Everyone loved her. There was no replacing her. So if I could get her back, or her personality traits, I would do anything to do that.”

The Shields reached out to PerPETuate, an animal genome preservation business run by Ron Gillespie, who used to work at the cattle genetics company ABS Global. Right now, he’s partnering with ViaGen, and recently, its laboratory delivered four clones sourced from a genome Gillespie first harvested in 2000. He happily preserved Gwen’s DNA, and the Shields family is currently deep in the cloning process, one Gillespie remains optimistic about.

“[Customers] see the whole procedure as a healing journey.”

“Dog owners [throughout history] have said, ‘This is the best dog I’ve ever had,’ and I’m going to breed them with another dog to get a puppy that’s as closed to [the original] as possible,” Gillespie says. “That’s a very natural, common thing. Selective breeding has been going on for years. This is the ultimate breeding tool. You’re not just getting half of the genes; you’re getting 100 percent of them. It’s an understandable step in the evolution of breeding.”

Gillespie’s currently working with a client with an autistic son who finds peace in the presence of an old family cat. The client is, of course, terrified of what might happen after the cat dies. He’s tried other animals (and other cats), but nothing musters the same pacifying effect. So instead, he holds out hope that maybe he can give his son some peace with a long line of duplicates.

“This cat is of exceptional value to this boy and to this family,” says Gillespie. “They tried the brother of this cat, and the boy totally rejected his brother. So they’re going to clone him. And what’s gonna happen? Is this cat gonna be able to substitute? If it is, think about the significance of that. People don’t think in those terms. They just think it’s just rich people with a lot of money.”

Gillespie tells me that 2017 has been one of the busiest years for PerPETuate since he started the business in ’98, and speculates eventually pet cloning will become more common as the prices get more affordable. He thinks ViaGen is a good first step, as they offer a cloning service domestically for $50,000a bargain compared to Sooam’s six-figure entry fee. But obviously, that price will have to come down quite a bit more for cloning to truly hit the mainstream.

In a way, Gillespie has been banking on cloning become more accessible for the entirety of his career, since his business is basically built around preserving genomes for an era where it does become more economically viable for the average pet lover. Until then, it’s not just the Diane von Furstenbergs of the world who are writing big checks to bring back their beloved pooches: As of the fall of ’15, Sooam Biotech estimated it had cloned some 600 dogs, not all of which had wealthy owners. Jae Woo Wang tells me some of their customers liquidate assets to afford the cloning process. Priorities tend to shift in the midst of grieving.

ViaGen’s testimonial section illustrates that, no matter the cost, its customers believe it’s money well spentdozens of former clients there have drafted sonnets in tribute of the preserved genomes of their dead pets and the hopes for the possible clones they may one day produce. “They see the whole procedure as a healing journey,” says Gillespie. “At first it’s very difficultyour dog just passed away, you have to go to a vet to get a biopsy done and send it over, or sometimes travel here. You have to wait for us to give the confirmation that the cells are OK. All of that is very, very stressful. But once they actually have the puppy, that’s when they unload.”

Michelle and Doug Shields just want their dog back, and look at the price tag as a worthy luxury. Some more time with Gwen is a far more important splurge to them than a trip to Italy or a Country Club membership. Michelle says that most of her friends understand, because they all loved Gwen too. “We’re just people who really love our dog,” Michelle says.

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In the Future, You Will Have the Same Pet Your Entire Life – VICE

Blind woman can’t go out alone because of everyday obstacles Dubliners create – The Irish Sun

Campaigner Lorraine Cooke wants people to be aware of the problems that even a inappropriately parked bike can cause for those with sight problems

A BLIND woman who cant go out without help says she hopes to eventually be able to go shopping by herself.

Campaigner Lorraine Cooke is afraid to use a cane after getting a fright while learning and her flat is too small for a guide dog.

News Group Newspapers Ltd

She said: Most people with visual impairment either rely on a dog, or a cane.

I tend to rely on a human because whenever I was doing my long cane training I came across a council bollard that was blocking the pavement, which pretty much knocked my confidence.

I began training at that late anyway, but no, long cane training was not an option for me. Im not an animal lover, but even if I was, the space in (my home) wouldnt sleep a dog.

It means that Lorraine, who was born with a rare eye condition, has to constantly rely on friends to get out of her home in Drumcondra, Dublin.

News Group Newspapers Ltd

She said: I have personal assistant that helps me, and I do have very good friends in the area as well.

But Lorraine, an independent spokeswoman for disabled people, hopes that doctors will eventually be able to fix her sight.

She said: I had a tiny little bit (of sight) whenever I was younger but none that I can remember and none that Im unlikely to get back any time soon unfortunately.

I was looking for stem cell treatment but my eye is too small to get it. Ive had too much surgery and too much damage and it was already damaged to begin with.

But Lorraine added that someday she hopes to venture out alone, saying: I would love to. Its only recently that Ive found out the news that I cant get stem cell treatment at this time.

I hope there will be a time, but at the same time Im trying to be realistic and make the most out of the supports I have.

Now Lorraine is backing a new public awareness campaign by that aims to make Dubliners aware how everyday actions can impact on the lives of blind people in the capital.

The adverts feature striking visuals such as a climbing wall in place of a badly parked car and a barbed wire fence in place of an overgrown hedge.

info@conormccabe.ie

It also shows a climbing frame in place of an on-street obstacle, such as an innocent sandwich board or bike.

Lorraine said: The main three things, are bikes, cars and branches. The campaign is just trying to encourage people to be aware.

info@conormccabe.ie

The Disability Federation of Ireland, the National Council for the Blind, Fighting Blindness, the Dublin Lord Mayor and Dublin City Council were also involved in putting the hard-hitting campaign together.

Lord Mayor Brendan Carr said: We want to raise awareness of how people can unthinkingly create major obstacles for people with disabilities.

Dublin City Council inspectors will now be policing on-street obstructions in the capital and working with local businesses in a bid to make the city more walkable for blind people.

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Blind woman can’t go out alone because of everyday obstacles Dubliners create – The Irish Sun

Dogs Get Pricey Stem Cell Therapy – livescience.com

Stem cell therapy is still years away for you, but for your pooch this modern medical procedure is now available.

Vet-Stem, a privately held company in San Diego, Calif., began offering fat-derived stem cell therapy this month for treatment of arthritis as well as tendon and ligament injuries in dogs. The pricy procedure uses an animal’s own fat to obtain adult stem cells, which are then injected into the problematic area to stimulate growth of healthy cells, spurring regeneration.

“We’ve seen stem cell therapy help dogs whose pain was previously so severe that they struggled to stand, jump into cars, chase balls or run up and down stairs,” said Robert Harman, DVM, and founder of Vet-Stem. Treatment cost ranges from $2,000 to $3,000. So far, the company has trained more than 100 board certified small animal veterinary surgeons nationwide to offer the procedure.

How it works About two tablespoons of fat, usually from the abdomen or shoulder blade area, are removed from an anesthetized dog for shipment to the company. Within 48 hours, the laboratory isolates stem and regenerative cells from the fat and ships them back to surgeons in ready-to-inject syringes. Cells are not engineered or modified in any way, the company says, and in dogs with osteoarthritis, extra cells are frozen in case re-treatment is necessary. Stem cells are known for their amazing ability to morph into any kind of tissue, but Harman says they do so much more. “A huge part of what they do is to provide growth factors and chemicals that help the injury heal,” he said. “It does so by reducing inflammation it actually blocks inflammatory molecules. They block scar tissue from forming and they recruit in all other kind of healing and stem cells from other places in the body, so they’re actually like a master healing cell.” Since 2004, the company says it has successfully treated 3,000 horses with tendon, ligament and joint injuries, with many going on to compete again at their prior level of performance.

About 200 dogs have been treated by the company in the past three years. Harman said the only side effect seen in a small number of cases is inflammation at the injection site, lasting a few days.

Other treatments

Soon other cutting-edge regenerative therapy might be available for canines. Veterinarian Richard Vulliet, a professor in the molecular biosciences department at the University of California, Davis, is studying to see if stem cells derived from bone marrow can treat degenerative myelopathy, a spinal cord disease affecting German shepherds and Pembroke Welsh Corgis.

Since the disorder is similar to multiple scoliosis, discoveries made in dogs could be applicable to people, he said.

No federal regulations are in place for stem cell treatment in animals so veterinarians can progress quickly to discover new applications.

“We can do more, better, faster and cheaper than a clinical medical trial in humans,” he said.

Within the next few weeks Vulliet plans to inject the first dogs in his study, suffering from degenerative spinal disease, with bone marrow stem cells. A successful outcome in those family pets and others could lead to a commercially available treatment as early as next year. As for fat stem cells, he said it’s too soon to tell if the therapy is safe. “You never want to be the first one to use a new treatment,” said Vulliet.

Tough decisions? The American Veterinary Medical Association (AVMA) in Schaumburg, Ill., which represents more than 76,000 veterinarians, fully supports the ethical use of stem cells for the benefit of animal health but admits its hard to keep up with the breathtaking pace of research and new treatments. “I don’t know that anyone in the AVMA has heard anything specific about how efficacious [Vet-Stems treatment] has been,” said veterinarian Elizabeth Sabin, the associations assistant director of education and research. “It’s just perhaps too new of a technology.”

Last week, the results of a double-blind control study by Vet-Stem which showed improved mobility in dogs with osteoarthritis was published in the journal Veterinary Therapeutics.

While some dog owners might want to take a wait and see approach, Vulliet said not everyone has the luxury of delaying treatment.

“It’s nice to say: ‘I’d wait a couple of years until this flushes out’ and I would except that you’ve got a real dog that has a real disease right now,” he said.

John Doyle, a dog trainer in Poway, Calif., is glad he didn’t wait. His border collie, Buzz, severed a rear tendon last year. The 2-year-old dog underwent surgery then had a series of three fat stem cell injections. Doyle’s veterinarian told him Buzz’s recovery could take a year practically an eternity for a high-energy dog that competes in sheep and cattle herding events internationally.

With Vet-Stem’s new therapy, recovery was much faster.

“In six weeks this dog was working again,” said Doyle. “It’s a stunning turnaround.”

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Dogs Get Pricey Stem Cell Therapy – livescience.com

Successful dog bone implant paves way for 3D-printed human limbs … – RT

Published time: 24 Jun, 2017 16:33

New bone regeneration technology that successfully implanted a bone in a dogs leg could pave the way for a revolutionary treatment that would see human bone implants generated by a 3D printer.

Researchers at the University of Glasgowin Scotland successfully saved a dogs leg from amputation by using medical technology funded by the landmine charity,Find A Better Way.

READ MORE: We made history: NASA launches lightest & first 3D-printed satellite, designed by Indian teen

The dog, Eva, broke her leg during a car accident and was close to needing an amputation when her vet contacted the synthetic bone research project.

Although patient trials were not due to start for a few more years, the researchers agreed to treat Eva using a combination of a naturally-occurring protein called BMP-2, combined with PEA, a common household ingredient found in paint and nail polish.

While BMP-2 is recognized as effective for stimulating the growth of bone tissue, scientists have had difficulty containing it in the relevant area.

However, project leader Professor Manuel Salmeron-Sanchez has discovered that PEA is effective in keeping the protein in position. He coated bone chips with the substance and the protein before placing the mixture in a two-centimeter gap in Evas front leg.

The team says its the first time PEA and BMP-2 have ever been used to treat anyone dog or man.

PEA has never been approved for medical use in humans. Although the project is seeking approval, this could take up to five years.

Find a Better Way announced a 2.8 million ($3.58mn) financial agreementwith the University of Glasgow last year with the aim of developing 3D printed limbs. The research is focused on generating synthetic bones through 3D printing, nanotechnology, and stem cell research.

Researchers have been encouraged by Evas full recovery and are working towards their final goal treatment for landmine blast survivors.

The treatment involves creating a 3D-printed medical-grade plastic bone scaffold, which is then covered with stem cells that generate bone at an accelerated rate, along with the BMP-2/PEA mixture. After the stem cells and BMP-2 grow bone tissue, the plastic scaffold biodegrades, leaving only the newly-grown bone in place.

The project says while the technology was initially designed to help treat landmine blast survivors, it has the potential to be used for anyone who needs new bone tissue.

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Successful dog bone implant paves way for 3D-printed human limbs … – RT